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A composition comprising the extract of Scutellaria baicalensis and the compound isolated therefrom for preventing and treating the viral disease caused by enterovirus
A composition comprising the extract of Scutellaria baicalensis and the compound isolated therefrom for preventing and treating the viral disease caused by enterovirus
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机译:包含黄cut提取物和从中提取的化合物的组合物,用于预防和治疗由肠病毒引起的病毒性疾病
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摘要
The present invention relates to a composition having an anti-enterovirus, and more particularly, to a composition comprising an extract of gold or a compound isolated therefrom as an active ingredient, which comprises (1) cytotoxicity in vero cells and EV71 , CVB3, CVA16, and cytopathic inhibition experiments; (2) Western blot analysis of the VP protein of enterovirus 71 to confirm antiviral activity against EV71; (3) Analysis of antiviral activity mechanism through replicon analysis using replicon system (pRibFluc-EV71); (4) In vitro tests and in vivo tests in vivo, such as in vivo animal experiments for the determination of antiviral activity against CVB3 virus using BALB / c mice, By confirming that the samples exhibit strong anti-enterovirus activity, the composition can be usefully used as a pharmaceutical composition or health functional food for the prevention and treatment of diseases caused by enteroviruses.
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