METHOD non-invasive diagnosis of portal hypertension in chronic diffuse liver diseases

摘要

A method for diagnosing portal hypertension in chronic diffuse liver diseases by measuring hemodynamic parameters in the portal and splenic vein by ultrasonic Doppler and of calculating congestion index in the portal vein, characterized in that as a result of blood tests and a liver biopsy tissue determined parameters biochemical activity, and morphological activity of liver disease on liver biopsy results, and then further congestion index calculated in splenic ve not (IZ ST) characterizing the severity of portal hypertension, in formula IZ ST = S ST / LCS CB where S NE - the cross-sectional area of ​​the splenic vein (SV), see, LCS SV - linear velocity of the blood flow in the splenic vein establish biochemical and hemodynamic parameters in the portal vein and splenic in healthy control subjects, these parameters are ordered in a table form, determines the degree of low, moderate or high morphological and biochemical activity in patients with liver disease, comparing them with parameter s biochemical activity in healthy individuals in the control group; and then correlate the index values ​​of stagnation in the portal and splenic vein with indicators of biochemical and morphological activity of liver disease in patients and in cases of excess stagnation index in the splenic vein at moderate biochemical and morphological activity of more than 0,015, and at high biochemical and morphological activity of more than 0,018 establish the presence portal hypertension, early, stage of disease dotsirroticheskoy.