首页> 外国专利> COMPOSITION FOR APPLICATION FOR STIMULATION OF ANGIOGENESIS IN THE INTESTINE, SUCTION OF NUTRIENTS AND TRANSFER OF ELECTRONIC NUTRITION, AND / OR FOR PREVENTION, AND / OR TREATMENT OF SLEEP AND SLEEP SUMMER

COMPOSITION FOR APPLICATION FOR STIMULATION OF ANGIOGENESIS IN THE INTESTINE, SUCTION OF NUTRIENTS AND TRANSFER OF ELECTRONIC NUTRITION, AND / OR FOR PREVENTION, AND / OR TREATMENT OF SLEEP AND SLEEP SUMMER

机译:用于在肠内刺激血管生成,吸收营养和转移电子营养,和/或预防和/或治疗睡眠和睡眠夏季的组合物

摘要

1. A composition comprising at least one long chain polyunsaturated fatty acid (LC-PUFA), at least one probiotic and a mixture of oligosaccharides, said mixture comprising at least one N-acetylated oligosaccharide, at least one sialylated oligosaccharide and at least one sialylated oligosaccharide and at least one sialylated oligosaccharide at least one neutral oligosaccharide, for use in stimulating angiogenesis in the intestine and absorption of nutrients, tolerance of enteral nutrition; and / or in the prevention and / or treatment of inflammatory bowel lesions, such as necrotizing enterocolitis; and / or recovering from damage and / or surgery in the intestine. 2. The composition of the preceding paragraph, wherein the neutral oligosaccharide is selected from fructooligosaccharides (FOS) and / or galactoligosaccharides (GOS), preferably galactooligosaccharides. 3. The composition of claim 1, wherein said oligosaccharide mixture contains at least one N-acetylated oligosaccharide selected from the group consisting of GalNAcα1,3Galβ1,4Glc (= 3′GalNAC-lac = N-acetyl-galactosaminyl-lactose), Galβ1, 6GalNAcα1,3Galβ1,4Glc (= 6′Gal-3GalNAc-lac = galactosyl-N-acetyl-galcatosaminyl-lactose), Galb1,4GlcNAcb1,3Galb1,4Glc (lacto-N-neotetraose, or LNnT1,3) and Galbb1,3l,3l 4Glc (lacto-N-tetraose, or LNT); at least one sialylated oligosaccharide selected from the group consisting of NeuAcα2,3Galβ1,4Glc (= 3′-sialyllactose) and NeuAcα2,6Galβ1,4Glc (= 6′-sialyllactose), and at least one neutral oligosaccharide selected from the group consisting of Galβ1,6Gal (= β1,6-digalactoside; Galβ1,6Galβ1,4Glc (= 6′-Gal-lac); Galβ1,6Galβ1,6Glc; Galβ1,3Galβ1,3Glc; Galβ1,3Galβ1,4Glc (= 3′Galc -lac); Galβ1,6Galβ1,6Galβ1,4Glc (= 6 ′, 6-diGal-lac); Galβ1,6Galβ1,3Galβ1,4Glc (= 6 ′, 3-diGal-lac); Galβ1,3Galβ1,6Galβ1,4Glc ( = 3 ′, 6-diGal-lac); Galβ1,3
机译:1.一种组合物,其包含至少一种长链多不饱和脂肪酸(LC-PUFA),至少一种益生菌和寡糖的混合物,所述混合物包含至少一种N-乙酰化的寡糖,至少一种唾液酸化的寡糖和至少一种唾液酸化的寡糖和至少一种唾液酸化寡糖,至少一种中性寡糖,用于刺激肠内血管生成和营养吸收,肠内营养耐受性;和/或用于预防和/或治疗炎症性肠病,例如坏死性小肠结肠炎;和/或从肠道损伤和/或手术中恢复过来。 2.前述段落的组合物,其中所述中性寡糖选自低聚果糖(FOS)和/或低聚半乳糖(GOS),优选低聚半乳糖。 3.权利要求1的组合物,其中所述寡糖混合物包含至少一种选自GalNAcα1,3Galβ1,4Glc(= 3'GalNAC-lac = N-乙酰基-半乳糖胺基-乳糖)的N-乙酰化寡糖,Galβ1, 6GalNAcα1,3Galβ1,4Glc(= 6'Gal-3GalNAc-lac =半乳糖基-N-乙酰基-半乳糖异氨基乳糖),Galb1,4GlcNAcb1,3Galb1,4Glc(乳糖-N-新四糖或LNnT1,3) 3l 4Glc(乳酸-N-四糖或LNT);至少一种选自NeuAcα2,3Galβ1,4Glc(= 3'-唾液酸乳糖)和NeuAcα2,6Galβ1,4Glc(= 6'-唾液酸乳糖)的唾液酸化寡糖,以及选自Galβ1的至少一种中性寡糖,6Gal(=β1,6-杜鹃花苷;Galβ1,6Galβ1,4Glc(= 6′-Gal-lac);Galβ1,6Galβ1,6Glc;Galβ1,3Galβ1,3Glc;Galβ1,3Galβ1,4Glc(= 3′Galc -lac) ;Galβ1,6Galβ1,6Galβ1,4Glc(= 6',6-diGal-lac);Galβ1,6Galβ1,3Galβ1,4Glc(= 6',3-diGal-lac);Galβ1,3Galβ1,6Galβ1,4Glc(= 3' ,6-diGal-lac);Galβ1,3

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