Sampling of biomarkers in the context of devices for neuromodulation and related systems and methods

摘要

1. A system comprising: an element for neuromodulation designed to modulate nerves located on the patient’s renal artery or otherwise close to it; an elongated trunk having a first part designed for intravascular placement, wherein the element for neuromodulation modulates nerves, and a second a part close to the first part, while the second part is designed for extracorporeal placement when the element for neuromodulation modulates the nerves; the occlusal element passing around the ne segment hand side; sampling port located distally from the first portion of segments; sampling cavity extending from a sampling port toward the second portion, an opening for inflating the occlusal element; and an inflation cavity extending from the inflation hole toward the second part. 2. The system of claim 1, further comprising an analyzer designed to analyze a biological sample from a patient for a biological parameter that changes in response to nerve modulation. The system according to claim 2, in which: the analyzer is functionally connected to the second part; The sampling chamber extends from the sampling port through the barrel to the analyzer. 4. The system of claim 2, further comprising a handle coupled to the second part, where the analyzer is carried by the handle. The system of claim 2, wherein the analyzer includes an indicator designed to indicate the status of a biological parameter, the modulation status of a nerve based on a biological parameter, or both. The system of claim 2, further comprising: perfusion input proximal to the occlusal e