Methods impact on the expression of alcohol dehydrogenase gene

摘要

1. Method for acting on expression of alcohol dehydrogenase gene into patient cells, comprising contacting said cells with one or more antisense oligonucleotides, wherein the sequence of at least 70% identical to the sequence of said gena.2. A method according to Claim. 1, where the expression povyshayut.3. A synthetic oligonucleotide, having a sequence 70% identical to a sequence alkogoldegidrogenazy.4 gene. A synthetic oligonucleotide according to claim. 3, wherein the oligonucleotide has a sequence 80% identical to the sequence alkogoldegidrogenazy.5 gene. A composition comprising one or more synthetic oligonucleotides of claim. 3.6. A method for treating a disease associated with the gene of alcohol dehydrogenase comprising administering to a patient an effective dose of whether the number of oligonucleotides according to claim. 3.