首页> 外国专利> N-Alkyl-tropanes, and N-alkyl-N-nortropiny with anticholinergic, neuroprotective, antiparkinsonian, antiepileptic, analgesic, antidepressant activity and antiaddiktivnoy

N-Alkyl-tropanes, and N-alkyl-N-nortropiny with anticholinergic, neuroprotective, antiparkinsonian, antiepileptic, analgesic, antidepressant activity and antiaddiktivnoy

机译:具有抗胆碱能,神经保护,抗帕金森病,抗癫痫药,镇痛药,抗抑郁药活性和抗成瘾性的N-烷基-托烷和N-烷基-N-嗜碱性

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to use of N-alkyl derivatives of tropine and nortropine of general formula (I) for treating Parkinson's disease, epilepsy, depression and pain. Invention also relates to a method of treating Parkinson's disease, epilepsy, depression and pain.;EFFECT: technical result is compounds of formula (I) have considerable advantages over mecamylamine, since they considerably surpass mecamylamine on H-cholinolytic, antiparkinsonian, antidepressant and analgesic activity.;3 cl, 12 tbl
机译:发明领域本发明涉及通式(I)的tropine和nortropine的N-烷基衍生物在治疗帕金森氏病,癫痫,抑郁和疼痛中的用途。发明还涉及治疗帕金森氏病,癫痫,抑郁和疼痛的方法。效果:技术结果是式(I)的化合物相对于美卡明胺具有相当大的优势,因为它们在H-胆碱分解,抗帕金森病,抗抑郁和镇痛药方面大大超过美卡明胺活动。; 3 cl,12汤匙

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