Methods impact on the expression of the gene APOE

摘要

1. Method for acting on expression of APOE gene in patient cells, comprising contacting said cells with one or more miRNA specific for an antisense oligonucleotide having a sequence at least 70% identical to a sequence of said gena.2. A method according to Claim. 1, where the expression ponizhayut.3. A composition comprising one or more miRNA specific for an antisense oligonucleotide having a sequence at least 70% sequence identity AROE.4 gene. A method for treating a disease associated with the APOE gene, comprising administering an effective dose of one or more miRNA specific for an antisense oligonucleotide having a sequence at least 70% identical to the sequence of the APOE gene.