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METHOD AND APPARATUS FOR RECEIVING VASODILATION DATA AS INDIVIDUAL'S LOCAL COETANEOUS THERMAL HYPEREMIC RESPONSE

机译:接收局部局部热瞬变热响应的血管舒缩数据的方法和装置

摘要

FIELD: medicine.SUBSTANCE: method for evaluating at least one vasodilation parameter as an individual's local coetaneous thermal hyperemic response, involves taking a basic measurement in a first area of individual's samples taking at a first temperature and generating a first basic red blood cell flow (RBCF) of the sampling area and measuring an individual's first base mean arterial pressure (P), increasing a temperature of the first sampling area from the first temperature to the second temperature, maintaining the second temperature for the initial heating period making from 2 to 14 minutes, and recording a range of the first initial RBCFs (RBCF) of the first sampling area in the range of time points (T) to determine the first initial maximum RBCF (RBCF,), and recording the individual's first initial mean arterial pressure (P) during the initial heating period, and calculating the vasodilation parameter, wherein the vasodilation parameter equals to or originates from a first initial maximum coetaneous vascular conductivity (CVC) calculated by formula: CVC= RBCF/P; the vasodilation parameter derived from the first CVC, is a measurement (ΔCVC) of the first initial maximum CVC, or an initial area under curve (initial AUC); ΔCVC is calculated by formula: ΔCVC = CVC- (RBCF/P), and for initial AUC, RBCFis marked against Tto plot a curve having a curve function of F(X); initial AUC is calculated by formula:wherein t equals to or exceeds RBCFmeasurement time. A laser Doppler apparatus comprises a user interface, laser Doppler detector, heating unit to heat the sampling area, laser Doppler detector and heating unit controller based on user input and default settings, computing unit, database containing a standard vasodilation parameter measured in a group of healthy individuals, and a comparator unit used to compare the individual's vasodilation parameter to the standard value.EFFECT: using the invention enables the higher measurement efficiency.10 cl, 2 dwg, 15 tbl, 8 ex
机译:领域:医学。物质:用于评估至少一个血管舒张参数作为个体的局部瞬性热充血反应的方法,涉及对在第一温度下采集的样本的第一区域进行基本测量,并产生第一基本红细胞流量( RBCF)并测量个人的第一基本平均动脉压(P),将第一采样区域的温度从第一温度提高到第二温度,并在初始加热期间保持第二温度从2升高到14分钟,并在时间点(T)的范围内记录第一采样区域的第一初始RBCF(RBCF)的范围,以确定第一初始最大RBCF(RBCF,),并记录个人的第一初始平均动脉压( P)在初始加热期间,并计算血管舒张参数,其中血管舒张参数等于或起源于第一初始最大头皮血管电导率(CVC)的计算公式为:CVC = RBCF / P;源自第一CVC的血管舒张参数是第一初始最大CVC的测量值(ΔCVC)或曲线下的初始面积(初始AUC); ΔCVC由以下公式计算:ΔCVC= CVC-(RBCF / P),对于初始AUC,用T标记的RBCFis绘制具有F(X)曲线函数的曲线;初始AUC由以下公式计算:其中t等于或超过RBCF测量时间。激光多普勒仪设备包括用户界面,激光多普勒探测器,加热采样区域的加热单元,基于用户输入和默认设置的激光多普勒探测器和加热单元控制器,计算单元,包含在一组中测量的标准血管舒张参数的数据库健康个体,以及用于将个体的血管舒张参数与标准值进行比较的比较器单元。效果:使用本发明可以实现更高的测量效率。10 cl,2 dwg,15 tbl,8 ex

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