METHOD FOR DETERMINING INDIVIDUAL RESPONSIVENESS OF HUMAN MITOCHONDRIA UNDER ACTION OF METABOLIC PREPARATIONS IN TESTS in vitro

摘要

FIELD: medicine.;SUBSTANCE: method involves conducting blood analysis and determining a mitochondrial fluorescence both in an initial state, and after adding a blood sample with an examined in vitro metabolic corrector in a dose equal to a recommended single dose, and calculating fluorescence gain rates. If the mitochondrial fluorescence gain rate under the action of the metabolic corrector is 0, the mitochondria are considered activated under the action of the metabolic corrector in a specific patient, whereas the derived gain rate of 0 enables to state the depressed mitochondrial function under the action of the metabolic corrector in a specific patient.;EFFECT: presented method enables to determine the patient's individual sensitivity to a specific metabolic corrector for the purpose of the individual selection of a medicinal product and further effective treatment of the patients suffering from ischemic heart disease.;1 ex, 5 dwg