首页> 外国专利> METHOD FOR DIAGNOSIS OF DISTURBED ENERGY METABOLISM OF LYMPHOCYTES WITH COMMUNITY-ACQUIRED PNEUMONIA IN CHILDREN

METHOD FOR DIAGNOSIS OF DISTURBED ENERGY METABOLISM OF LYMPHOCYTES WITH COMMUNITY-ACQUIRED PNEUMONIA IN CHILDREN

机译:诊断社区获得性肺炎淋巴细胞的能量代谢紊乱的方法

摘要

FIELD: medicine.;SUBSTANCE: invention can be used for assessing degree of breakdown of energy metabolism blood lymphocytes in children with community-acquired pneumonia (CAP). For this purpose, flow cytometry is used for accounting of lymphocytes with reduced membrane potential of mitochondria. With values from 0 to 35% normal level is diagnosed, 36 to 75% - subcompensated disorder, not requiring specific therapy, 76% and more - decompensated disorders requiring in complex treatment of community-acquired pneumonia assignment of en-ergotropic preparations.;EFFECT: using the given method enables detecting the disturbed cell supply at earlier stage, if no changes succinate dehydrogenase activity, which enables its use in clinical practice for separation of the risk groups of children with CAP requiring metabolic correction.;1 cl, 1 tbl, 4 ex
机译:领域:药物;发明:本发明可用于评估社区获得性肺炎(CAP)患儿能量代谢血淋巴细胞的分解程度。为此目的,流式细胞仪用于检查线粒体膜电位降低的淋巴细胞。诊断值为0到35%的正常水平,需要综合治疗的社区获得性肺炎分配需要复杂治疗的36%到75%的亚代偿性失调,不需要特定的治疗,76%甚至更高的失代偿性失调。 :使用给定的方法能够在不改变琥珀酸脱氢酶活性的情况下及早发现受干扰的细胞供应,从而使其在临床实践中可用于分离需要代谢校正的CAP儿童的危险组。1cl,1 tbl, 4前

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