FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology and represents a recombinant microorganism of genus Escherichia, having enhanced ability to produce L-tryptophan, where said recombinant microorganism is modified by deletion, partially or completely, of leader peptide, having a nucleotide sequence SEQ ID NO: 2, in regular expression area having a nucleotide sequence SEQ ID NO: 1, on endogenous tryptophan operon. Invention also relates to a method of producing L-tryptophan using said microorganism.;EFFECT: invention enables to obtain L-tryptophan with high efficiency.;10 cl, 3 dwg, 6 tbl, 11 ex
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机译:技术领域本发明涉及生物技术并且代表具有增强的生产L-色氨酸能力的埃希氏菌属的重组微生物,其中所述重组微生物通过部分或完全缺失具有核苷酸序列的前导肽而被修饰。 SEQ ID NO:2,在内源性色氨酸操纵子上具有核苷酸序列SEQ ID NO:1的规则表达区域中。本发明还涉及使用所述微生物生产L-色氨酸的方法。效果:本发明能够高效地获得L-色氨酸。10 cl,3 dwg,6 tbl,11 ex
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