MONO-TERPENE DERIVATIVES OF CHALCONE OR DIHYDROCHALCONE AND USE THEREOF AS ANTI-PIGMENTING AGENTS

摘要

FIELD: pharmaceutics.;SUBSTANCE: invention relates to pharmaceutical industry, specifically to extract of Helichrysum gymnocephalum (DC) Humbert for inhibiting melanin synthesis, which contains molecules of formula (I) in a certain amount per 100 g of dry substance extract ; ;where ; - a single bond or double bond; R1 = H or CH₃ and R2 = H or OH. Method of producing Helichrysum gymnocephalum (DC) Humbert including certain steps. Application for cosmetic purposes of plant extract, belonging to a certain genus containing molecules of formula (I) in a certain amount. Composition for inhibiting melanin synthesis, containing an active substance of extract of certain plants and molecules of formula (I) in a certain amount. Application of cosmetic composition for relieving and/or removal and/or prevention of pigment spots on skin and for bleaching and/or skin lightening and/or bristle and/or hair. Cosmetic method for bleaching and/or skin lightening and/or bristle and/or hair, involving coating the skin and/or bristle and/or hair, as well as a cosmetic method for relieving and/or removal and/or prevention of pigment spots on the skin. Molecule of formula (VI) .;EFFECT: invention is characterised by high activity for decreasing pigmentation.;22 cl, 1 tbl, 6 ex