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Rapidly disintegrating tablets without disintegration accelerators

机译:无需崩解促进剂即可快速崩解片剂

摘要

Solid pharmaceutical composition is in the form of directly plastic films compressed, quickly limit of resolution of the transmitter tablets for the production of a drinking solution and / or for oral application containing:(a) at least 60 w -% of one or more water-soluble auxiliaries selected from the group consisting of spray - of agglomerated, directly compressible sugar and / or sugar alcohols;(b) 1 to 10 w -% crystalline ascorbic acid;(c) optionally up to 5 w -% of a water soluble zinc compound;(d) optionally also one or more other water-soluble additives selected from the group consisting of natural and / or synthetic sweeteners, taste-improving agents, flavorings, plant extracts, plants concentrates, plants powder and acids obtained with;(e) in addition optionally magnesiumdicitrat; as well as(f) a maximum of 0,01 w -% of one or more explosive selected from the group consisting of crosslinked sodium carboxymethylcellulose, cross-linked polyvinylpyrrolidone, crosslinked sodium carboxymethyl starch, starch, microcrystalline cellulose, crosslinked alginic acid, ion exchange resins, gellan, xanthan and soya, - polysaccharides; and(g) a maximum of 0,01 w -% of effervescent additives such as sodium bicarbonate and citric acid.
机译:固体药物组合物为直接压缩的塑料薄膜形式,迅速限制了传输片剂的分辨率,可用于生产饮用溶液和/或用于口服,其中包含:(a)至少60 w%的一种或多种水-选自以下的可溶性助剂:-可凝结的可直接凝结的糖和/或糖醇的喷雾-(b)1至10 w-%的结晶抗坏血酸;(c)任选至多5 w-%的水溶性锌化合物;(d)任选地还一种或多种其他水溶性添加剂,它们选自天然和/或合成甜味剂,增味剂,调味剂,植物提取物,植物浓缩物,植物粉和用其制得的酸; e)另外任选地除镁;以及(f)最多0.01 w-%的一种或多种选自交联羧甲基纤维素钠,交联聚乙烯吡咯烷酮,交联羧甲基淀粉钠,淀粉,微晶纤维素,交联藻酸,离子的炸药交换树脂,结冷胶,黄原胶和大豆,-多糖; (g)最多0.01 w-%的泡腾添加剂,例如碳酸氢钠和柠檬酸。

著录项

  • 公开/公告号DE202015004009U1

    专利类型

  • 公开/公告日2016-01-11

    原文格式PDF

  • 申请/专利权人 HERMES ARZNEIMITTEL GMBH;

    申请/专利号DE20152004009U

  • 发明设计人

    申请日2015-06-09

  • 分类号A61K31/375;

  • 国家 DE

  • 入库时间 2022-08-21 14:09:09

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