The signature is a continuation of the nail subject of the skins asian actinic

摘要

The present invention relates to a signature of the nail specific molecular actinic skin, asian, comprising the genes lce3d, sprr2b, sprr2g and sprr3, and various applications of this signature. In particular, the invention concerns a method of characterization of a spot visible pigment in humans with a skin asian, comprising the comparison of the levels of expression, in the skin samples coming from said spot and skin adjacent not damaged, the genes. The present invention also relates to methods for evaluating the efficacy of a specific processing of the nail is present on an actinic skin asian, methods of treatment of actinic nail present on the skin, asian, as well as various modulators of the said genes and their use.