Embodiments of the invention are directed to compounds that inhibit an activity of EP AC proteins and methods of using the same. The inventors have developed a sensitive and robust high throughput screening (HTS) assay for the purpose of identifying EPAC specific inhibitors (Tsalkova et al. (2012) PLOS ONE 7(1):e30441).
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机译:本发明的实施方案涉及抑制EP AC蛋白活性的化合物及其使用方法。发明人已经开发了灵敏且鲁棒的高通量筛选(HTS)测定法,以鉴定EPAC特异性抑制剂(Tsalkova等人(2012)PLOS ONE 7(1):e30441)。
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