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METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY HCG ASSAY
METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY HCG ASSAY
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机译:HCG分析预测受试者妊娠结局的方法
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摘要
A method for predicting pregnancy outcome in a subject by determing the amount of EPMI-hCG in a sample from the subject using B152 antibody produced by the hybridoma cell line deposited with the American Type Culture Collection under Designation No. HB-12467; and a second, labelled antibody which binds to the complex formed by B152 antibody and EPMI-hCG to determine the amount of EPMI-hCG in the sample; using a third antibody which binds to intact, non-nicked hCG; and a fourth, labelled antibody which binds to intact non-nicked hCG simultaneously with the third antibody to determine the amount of intact hCG in the sample; and comparing the amount of EPMI-hCG in the sample with either the amount of EPMI-hCG determined in a sample from a temporally matched, normal pregnant subject or a non-pregnant subject, wherein an amount of EPMI-hCG in the subject's sample similar to the amount of EPMI-hCG in the sample from the temporally matched, normal pregnant subject or non-pregnant subject respectively indicates a positive or negative outcome of the pregnancy.
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