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ANTIBODIES DIRECTED TO ANGIOPOIETIN-LIKE PROTEIN 4 AND USES THEREOF
ANTIBODIES DIRECTED TO ANGIOPOIETIN-LIKE PROTEIN 4 AND USES THEREOF
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机译:直接作用于血管生成素样蛋白4的抗体及其用途
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摘要
Antibodies directed to the antigen ANGPTL4 and uses of such antibodies. In accordance with the teachings herein, there are provided fully human monoclonal antibodies directed to the antigen ANGPTL4. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
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