首页> 外国专利> CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS

CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS

机译：半胱氨酸和半胱氨酸前体药物可治疗精神分裂症并减少药物裂解

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摘要

The present invention provides cysteine and cystine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and compositions for treatment of schizophrenia and drug addiction. Exemplary prodrugs include the cysteine compound having the formula as well as cystine dimers thereof.

机译：本发明提供了用于治疗精神分裂症和药物成瘾的半胱氨酸和胱氨酸前药。本发明进一步包括含有前药的药物组合物，以及使用该前药和组合物治疗精神分裂症和药物成瘾的方法。示例性前药包括具有下式的半胱氨酸化合物及其半胱氨酸二聚体。

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公开/公告号EP2252596B1

专利类型
公开/公告日2016-12-28

原文格式PDF
申请/专利权人 MARQUETTE UNIVERSITY;UNIVERSITY OF WISCONSIN-MILWAUKEE RESEARCH FOUNDATION;
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申请/专利号EP20090707256
发明设计人 COOK JAMES M.;BAKER DAVID A.;YIN WENYUAN;JOHNSON EDWARD MERLE II;
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申请日2009-02-09
分类号C07D241/08;C07D487/04;A61K31/095;A61K31/4965;A61K31/4985;C07C321/14;C07C321/16;C07C327/26;A61P25/18;
国家 EP
入库时间 2022-08-21 14:05:51

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