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METHODS FOR PREDICTING CLINICAL OUTCOMES IN SUBJECTS AFFLICTED WITH ULCERATIVE COLITIS

机译:预测溃疡性结肠炎患者临床预后的方法

摘要

The present invention provides methods for predicting clinical outcome from a sample of a subject having ulcerative colitis (UC), comprising determining a prognostic marker profile and classifying the subject as either a responder or a non-responder. The methods can be used to monitor and to predict the progression of UC, by determining the likelihood for UC to progress either rapidly or slowly in an individual based on the presence or level of at least one marker in a sample. The methods can also be used to predict the regression of UC, by determining the likelihood for UC to regress either rapidly or slowly in an individual.
机译:本发明提供了从患有溃疡性结肠炎(UC)的受试者的样品中预测临床结果的方法,包括确定预后标志物谱并将该受试者分类为反应者或无反应者。通过基于样品中至少一种标记物的存在或水平确定个体中UC快速或缓慢进展的可能性,所述方法可用于监测和预测UC的进展。通过确定个体中UC迅速或缓慢消退的可能性,这些方法还可用于预测UC的消退。

著录项

  • 公开/公告号EP3210027A1

    专利类型

  • 公开/公告日2017-08-30

    原文格式PDF

  • 申请/专利权人 NESTEC S.A.;

    申请/专利号EP20150793908

  • 发明设计人 SINGH SHARAT;JAIN ANJALI;

    申请日2015-10-20

  • 分类号G01N33/68;

  • 国家 EP

  • 入库时间 2022-08-21 14:03:41

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