MEANS AND METHODS FOR ACCELERATED BREEDING BY INDUCING TARGETED STIMULATION OF MEIOTIC RECOMBINATION

摘要

The present invention generally relates to fusion proteins, nucleic acids, vectors, host cells carrying the fusion proteins or nucleic acids or vectors of the present invention for expressing the fusion proteins of the present invention, methods and kits to increase the rate of meiotic recombination and to specifically target meiotic recombination to a specific locus in a meiotic cell such as, e.g., a meiotic plant cell. The invention relates to fusion proteins comprising a zinc finger domain, which is operably linked via its N-terminus to the C-terminus of a SPO11 polypeptide, wherein the zinc finger domain comprises six or more zinc finger modules.