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APPARATUS FOR ANALYZING INDIVIDUAL CELLS OR PARTICULATES IN A BLOOD SAMPLE BASED ON FLUORESCENCE AND OPTICAL DENSITY IMAGES OF THE SAMPLE

机译:基于荧光和样品的光学密度图像分析血液样品中的单个细胞或微粒的装置

摘要

An apparatus (44) for analyzing a blood sample comprises a chamber (10) configured to quiescently hold the blood sample; an illuminator (46) configured to illuminate the blood sample along one or more fluorescent excitation wavelengths and one or more absorption wavelengths; an image dissector (48) configured to image at least a portion of the blood sample, and produce image signals representative of fluorescent emissions from, and optical density of, first constituents and second constituents disposed within the blood sample, which first constituents are different from the second constituents; and an analysis device (50) configured to determine one or more fluorescent emission values for each of the first constituents and second constituents using the image signals, and adapted to determine one or more optical density values for each of the first constituents and second constituents using the image signals, and adapted to identify the first constituents and the second constituents using the determined fluorescent emission and optical density values.
机译:用于分析血液样本的设备(44)包括:腔室(10),该腔室(10)构造成静态地保持血液样本;照明器(46),其配置为沿一个或多个荧光激发波长和一个或多个吸收波长照明血液样本;图像解剖器(48),其被配置为对血液样本的至少一部分成像,并产生表示来自血液样本内的第一成分和第二成分的荧光发射和光密度的图像信号,该第一成分与第二成分不同。第二个成分;分析装置(50),其被配置为使用所述图像信号来确定所述第一成分和第二成分中的每一个的一个或多个荧光发射值,并且适于使用以下方法来确定所述第一成分和第二成分中的每一个的一个或多个光密度值:图像信号,并且适于使用所确定的荧光发射和光密度值来识别第一成分和第二成分。

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