首页> 外国专利> MICROORGANISM HAVING ADJUSTED EXPRESSION OF R-SPECIFIC ENOYL-COA HYDRATASE GENE, AND METHOD FOR MANUFACTURING POLYHYDROXYALKANOATE COPOLYMER USING SAME

MICROORGANISM HAVING ADJUSTED EXPRESSION OF R-SPECIFIC ENOYL-COA HYDRATASE GENE, AND METHOD FOR MANUFACTURING POLYHYDROXYALKANOATE COPOLYMER USING SAME

机译:具有特定R表达的烯丙基-COA加氢酶基因表达的微生物,以及使用相同的方法制备聚羟烷基酸酯共聚物的方法

摘要

This invention relates to a microorganism that produces a polyhydroxyalkanoate (PHA) copolymer with a regulated monomer composition ratio and comprises a (R)-specific enoyl-CoA hydratase gene in the genome DNA, wherein a nucleotide sequence upstream of the (R)-specific enoyl-CoA hydratase gene comprises a modification consisting of a substitution(s), a deletion(s), an insertion(s), and/or an addition(s) of one or a plurality of nucleotides so that the expression of the (R)-specific enoyl-CoA hydratase gene is regulated, and to a method for producing a PHA copolymer using the microorganism.
机译:本发明涉及一种微生物,该微生物产生具有调节的单体组成比的聚羟基链烷酸酯(PHA)共聚物,并且在基因组DNA中包含(R)-特异性烯酰-CoA水合酶基因,其中(R)-特异性上游的核苷酸序列烯酰辅酶A水合酶基因包含一个或多个核苷酸的取代,缺失,插入和/或添加组成的修饰,因此(本发明涉及R)特异性烯酰辅酶A水合酶基因的调控,以及使用该微生物生产PHA共聚物的方法。

著录项

  • 公开/公告号EP3101129A1

    专利类型

  • 公开/公告日2016-12-07

    原文格式PDF

  • 申请/专利权人 KANEKA CORPORATION;

    申请/专利号EP20150742617

  • 申请日2015-01-30

  • 分类号C12N15/09;C12N1/21;C12P7/62;

  • 国家 EP

  • 入库时间 2022-08-21 14:02:07

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