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Platform and method for analyzing genetic, age and environmental influences in stimulus response studies using induced pluripotent stem cells

机译:使用诱导性多能干细胞在刺激反应研究中分析遗传,年龄和环境影响的平台和方法

摘要

Platform and method for conducting stimulus response studies in induced pluripotent stem cells derived from cells collected from donors or cells differentiated therefrom. Samples are taken at various ages and / or before and after exposure to environmental conditions. A method of preparing a platform is also provided. In one embodiment, multiple donors are involved. In another embodiment, the pluripotent pluripotent stem cells are differentiated. Optionally, the induced pluripotent stem cells or differentiated cells thereof are preserved for later analysis.
机译:在诱导的多能干细胞中进行刺激反应研究的平台和方法,所述的多能干细胞来源于从供体收集的细胞或由此分化的细胞。在不同年龄和/或暴露于环境条件之前和之后采集样品。还提供了一种准备平台的方法。在一实施方案中,涉及多个供体。在另一个实施方案中,多能多能干细胞是分化的。任选地,保存诱导的多能干细胞或其分化的细胞用于以后的分析。

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