DNA vaccine composition for preventing and treating herpes zoster and method for activating T cell against VZV antigen using the same

摘要

The present invention relates to a DNA vaccine composition for preventing and treating herpes zoster comprising at least one plasmid containing an insertion site of a VZV-derived gene encoding a herpes zoster virus (VZV) protein, and another pharmaceutically acceptable component. I will provide a. The plasmid includes a plurality of plasmids containing different heterologous gene insertion sites. The plasmid includes a first plasmid containing an insertion site of a first gene encoding IE-62 protein (Sequence Listing 1), and a second plasmid containing an insertion site of a second gene encoding IE-63 protein (Sequence Listing 2). And a third plasmid containing an insertion site for a third gene encoding the gE protein (Sequence Listing 3).