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Biochemical markers for lung and other diseases

机译:肺和其他疾病的生化标记

摘要

A bioassay method for quantification of peptide fragments elevated in pulmonary diseases such as COPD, SCC, or IPF, comprising a neoepitope formed at the cleavage site by cleaving elastin with a proteinase in vivo, comprising: Is contacted with an antibody having a specific binding affinity for the neoepitope amino acid sequence and a step of determining the level of binding, wherein the antibody comprises a terminal sequence ......... FGPGVV ......... VPGLGV IKAPKL ... A method that binds to one of the following and antibodies and immunoassay kits used in such a method.
机译:一种定量测定在肺部疾病(如COPD,SCC或IPF)中升高的肽片段的生物测定方法,包括通过在体内用蛋白酶裂解弹性蛋白在裂解位点形成的新表位,包括:与具有特异性结合亲和力的抗体接触用于新表位氨基酸序列的测定和确定结合水平的步骤,其中所述抗体包含末端序列……FGPGVV…………VPGLGV IKAPKL……与以下方法之一结合,并在这种方法中使用抗体和免疫分析试剂盒。

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