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Clinical multidisciplinary tool for diagnosis of insulinoma before and during surgery

机译:用于手术前和手术中胰岛素瘤诊断的临床多学科工具

摘要

The compound has the general formula: Ex4-linker-Sar (64Cu) -Fl (where Ex4 is an exendin-4 analog; the linker is formed of a polyethylene glycol (PEG) chain, eg, four ethylene glycol residues. Yes; Fl is a photoluminescent moiety, and Sar (64Cu) is a copper-64 atom chelated to a sarcofazine moiety) for detection and localization of insulinoma cells and beta cell populations Useful as a multidisciplinary imaging agent.
机译:该化合物的通式为:Ex4-接头-Sar(64Cu)-F1(其中Ex4是exendin-4类似物;接头由聚乙二醇(PEG)链形成,例如四个乙二醇残基。用于检测和定位胰岛素瘤细胞和β细胞群的Sar(64Cu)是与sarcofazine部分螯合的铜64原子),可用作多学科成像剂。

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