Detection of hypervariable regions between sets of protein sequences representing phenotypes of pairs

摘要

A computer-based bioinformatics method for identifying protein sequence differences between sets of sequences grouped into different phenotypic data sets, comprising: querying a database to determine a first phenotypic data set of protein sequences Identifying a consensus sequence motif within another phenotypic data set, calculating a pairwise correlation in the motif for each dataset, and calculating a change between the datasets to determine a 1 And correlating it with the phenotype of the data set by identifying one or more motifs (FIG. 1).(FIG.