首页> 外国专利> Enzyme having hydrolysis action on glycerol-3-phosphodiester such as glycerol-3-phosphocholine (GPC) and method for producing the same

Enzyme having hydrolysis action on glycerol-3-phosphodiester such as glycerol-3-phosphocholine (GPC) and method for producing the same

机译:对甘油-3-磷酸二酯具有水解作用的酶,例如甘油-3-磷酸胆碱(GPC)及其制备方法

摘要

PROBLEM TO BE SOLVED: To provide a novel enzyme having a hydrolytic action to a glycerol-3-phosphodiester such as a glycerol-3-phosphocholine (GPC), and to provide a production method of the same.SOLUTION: An enzyme (GPC-CP) with a hydrolytic action to a glycerol-3-phosphodiester includes either: a polypeptide containing a specific amino acid sequence; a polypeptide containing an amino acid sequence in which one or a plurality of amino acids are substituted, inserted, deleted and/or added in the specific amino acid sequence, and having hydrolytic activity; or a polypeptide having at least 80% of homology with the specific amino acid sequence, and having hydrolytic activity.
机译:解决的问题:提供一种对甘油-3-磷酸二酯具有水解作用的新型酶,例如甘油-3-磷酸胆碱(GPC),并提供其生产方法。解决方案:一种酶(GPC-具有对甘油-3-磷酸二酯的水解作用的CP)包括以下任一种:含有特定氨基酸序列的多肽;和一种多肽,其含有在特定氨基酸序列中取代,插入,缺失和/或添加一个或多个氨基酸的氨基酸序列,并且具有水解活性;或与特定氨基酸序列具有至少80%同源性并具有水解活性的多肽。

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