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Ophthalmologic measurement method, ophthalmic measurement apparatus and evaluation method of a test substance

机译:眼科测定方法,眼科测定装置以及被检物质的评价方法

摘要

PROBLEM TO BE SOLVED: To provide a novel method for ophthalmologic measurement taking account of wettability of the cornea, and to provide an ophthalmologic measuring apparatus, and a method for evaluating a test piece.SOLUTION: A method for ophthalmologic measurement includes: after administering an indicator substance to a subject's eye; causing the subject to blink and uniformly diffusing the indicator substance on the cornea; chronologically photographing the cornea surface on which a thin film of the indicator substance is formed; measuring a dry spot area on the basis of a plurality of images obtained by photographing; calculating a rise curve of the dry spot area from the measured dry spot area and calculating an inclination of an inflection point of the rise curve; and outputting a time taken from the blinking to an occurrence of the dry spot, the inclination of the inflection point of the rise curve, and a maximum dry spot area. An evaluation taking account of the tear liquid stability and the wettability of the cornea can be thus calculated.
机译:解决的问题:提供一种考虑到角膜的润湿性的眼科测量的新方法,提供一种眼科测量设备和一种用于评估试件的方法。解决方案:眼科测量的方法包括:在给药后指示物对受试者眼睛的指示;使受试者眨眼并使指示剂均匀分散在角膜上;按时间顺序拍摄形成指示物质薄膜的角膜表面;基于通过拍摄获得的多个图像来测量干斑面积;根据测得的干斑面积计算出干斑面积的上升曲线,并计算该上升曲线的拐点的倾斜度;输出从眨眼到出现干斑所需的时间,上升曲线的拐点的倾斜度以及最大干斑面积。由此可以计算出考虑到泪液稳定性和角膜的润湿性的评估。

著录项

  • 公开/公告号JP6169375B2

    专利类型

  • 公开/公告日2017-07-26

    原文格式PDF

  • 申请/专利权人 学校法人北里研究所;

    申请/专利号JP20130042732

  • 发明设计人 中西 基;

    申请日2013-03-05

  • 分类号A61B3/10;

  • 国家 JP

  • 入库时间 2022-08-21 13:55:58

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