Application of immune cells including CD54 expression reporter system and novel clonal cells

摘要

The present invention provides a method of confirming an immunoregulation substance, comprising: (a) providing a to-be-measured substance and an immune cell, wherein the immune cell includes a CD54 expression reporting system, and the CD54 expression reporting system comprises a CD54 gene promoter and a reporter gene connected with the CD54 gene promoter and used for reporting expression of the CD54 gene promoter; (b) processing the immune cell by the to-be-measured substance, and (c) measuring the product of the reporter gene produced by the immune cell processed by the to-be-measured substance so as to determine whether the to-be-measured substance has an immune regulation function.