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Novel steroid 11β-hydroxylase and method for producing 11β-hydroxysteroid using the same
Novel steroid 11β-hydroxylase and method for producing 11β-hydroxysteroid using the same
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机译:新型类固醇11β-羟化酶及使用该酶生产11β-羟类固醇的方法
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摘要
PROBLEM TO BE SOLVED: To provide a new steroid 11-hydroxylase useful for producing a 11-hydroxysteroid such as a hydrocortisone.SOLUTION: There is provided a protein of (a1), (b1) or (c1): (a1) a protein including a specific amino acid sequence, (b1) a protein including an amino acid sequence in which one or some amino acids are deleted, substituted or added in a specific amino acid sequence, and having steroid 11-hydroxylation activity, (c1) a protein including an amino acid sequence with a sequence identity of not less than 90% to a specific amino acid sequence, and having steroid 11-hydroxylation activity.
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