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Novel functionalized 5- (phenoxymethyl) -1,3-dioxane analogs exhibiting cytochrome P450 inhibition

机译:新型功能化的5-(苯氧甲基)-1,3-二恶烷类似物表现出细胞色素P450抑制作用

摘要

The pharmaceutical composition described in this document includes metabolic syndrome, obesity, headache, depression, hypertension, diabetes mellitus, Cushing syndrome, pseudo-Cushing syndrome, cognitive dysfunction, dementia, heart failure, renal failure, psoriasis, 5- (phenoxymethyl) has a disease-modifying action in the treatment of diseases associated with the production of cortisol, including glaucoma, cardiovascular disease, cancer, stroke, incidental tumors, or any disease involving excessive production of cortisol Includes -1,3-dioxane analogs.
机译:本文档中描述的药物组合物包括代谢综合征,肥胖,头痛,抑郁,高血压,糖尿病,库欣综合征,假库欣综合征,认知功能障碍,痴呆,心力衰竭,肾衰竭,牛皮癣,5-(苯氧甲基)在与皮质醇产生相关的疾病(包括青光眼,心血管疾病,癌症,中风,偶发性肿瘤或涉及皮质醇产生过多的任何疾病)的治疗中的疾病改变作用,包括-1,3-二恶烷类似物。

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