Cancer cell target vector, method for expressing a target gene specifically for cancer cells, and use for expressing a target gene specifically for cancer cells

摘要

Means that target gene expression is low in normal cells and can be expressed specifically in cancers derived from various organs, and a method for expressing the target gene specifically in cancer cells using the same The issue is to provide. The solution includes (A) a promoter cassette comprising a regulatory sequence and a core promoter sequence, and (B) a cancer cell target vector comprising a target gene sequence under its control, wherein the promoter cassette (A) comprises The present invention provides a cancer cell targeting vector comprising at least one element sequence that specifically reacts with deregulated E2F in a control sequence.