Myostatin inhibitory peptide

摘要

[Problem] To provide a therapeutic drug that exhibits a strong, selective inhibitory activity against myostatin, and enables muscle hyperplasia and an increase in muscle mass. [Solution] A peptide selected from (a)-(d), below, or a pharmaceutically acceptable salt thereof: (a) peptides having an amino acid sequence represented by one of SEQ ID NO: 1-9 or by SEQ ID NO: 40; (b) peptides having a length of 30 amino acids or less and including an amino acid sequence represented by one of SEQ ID NO: 1-9 or by SEQ ID NO: 40; (c) peptides that selectively inhibit the activity of myostatin and have an amino acid sequence represented by one of SEQ ID NO: 1-9 or by SEQ ID NO: 40 in which 1-6 amino acids have been substituted, deleted or added; and (d) derivatives of a peptide from any of (a)-(c), above.