Corneal epithelial disorder treatment for eye drops

摘要

PROBLEM TO BE SOLVED: To provide a multi-dose type eye drop for corneal epithelial defect treatment containing hyaluronic acid at a high concentration of ≥0.3 w/v%, which has low cytotoxicity, is effectively prevented from decomposing thereby having high preservation efficacy and which has low irritation and satisfactory sense of use.;SOLUTION: The multi-dose type eye drop for corneal epithelial defect treatment contains the following (a) to (c): (a) hyaluronic acid or its pharmacologically acceptable sa (b) boric acid and/or borax; and (c) composed of the following (c1) and/or (c2): (c1) chlorhexidine or its pharmacologically acceptable sa and (c2) p-hydroxy-benzoateester, wherein the blending quantity of the (a) hyaluronic acid or it pharmacologically acceptable salt is ≥0.3 w/v% to the whole of the formulation.;COPYRIGHT: (C)2012,JPO&INPIT