Orally administered preparations masking the bitterness of drugs with bitterness

摘要

Drugs with bitterness, e.g. silodosin, a drug with a very strong bitterness, can be taken without water and without water, and it has a dissolution property that can reproduce blood concentrations effective for treating urination disorders associated with prostatic hypertrophy. Provided is a novel preparation for oral administration (especially an intraoral rapidly disintegrating preparation). The present invention relates to masking particles obtained by granulating or coating drug particles containing a drug having a bitter taste (for example, silodosin) with a coating agent containing methyl methacrylate-diethylaminoethyl methacrylate copolymer. A masking particle having a methyl methacrylate-diethylaminoethyl methacrylate copolymer content of 80 to 400 parts by mass with respect to 100 parts by mass of a bitter drug (for example, silodosin) and a novel containing the masking particle Orally administered preparations and the like.