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Novel crystal mixture of levonorgestrel and process for producing the same
Novel crystal mixture of levonorgestrel and process for producing the same
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机译:左炔诺孕酮的新型晶体混合物及其制备方法
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摘要
In the powder X-ray diffraction spectrum, the levonorgestrel crystal mixture has a crystal polymorphism α of levonorgestrel having a diffraction peak at the diffraction angle (α) represented by 2θ below, and a diffraction angle (β ) And a crystal polymorph β of levonorgestrel having a diffraction peak. The ratio (weight ratio) between the crystalline polymorph α and the crystalline polymorph β may be the former / the latter = 5/95 to 90/10. (Α): 17.2 ° ± 0.2 °, 18.6 ° ± 0.2 °, 22.7 ° ± 0.2 °, 31.1 ° ± 0.2 ° and 35.5 ° ± 0 .2 ° (β): 13.9 ° ± 0.2 °, 14.5 ° ± 0.2 °, 21.3 ° ± 0.2 °, 24.9 ° ± 0.2 ° and 28.2 ° ± 0.2 ° This levonorgestrel crystal mixture is useful as an emergency contraceptive.
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