ANTITUMOR ACTIVITY OF MULTI-KINASE INHIBITORS IN TRIPLE NEGATIVE BREAST CANCER

摘要

A composition comprisinga) a compound of Formula (I), where R₁, R₂, and R₃ are, each one and independently, hydrogen or a protector group, wherein said protector group may consist of an alkyl group, a cycloalkyl group, a heterocyclic cycloalkyl group, a hydroxyalkyl group, a halogenated alkyl group, an alkoxyalkyl group, an alkenyl group, an alkynyl group, an aryl group, a heterocyclic aryl group, an alkylaryl group, an ester group, a carbonate group, a carboxylic acid group, an aldehyde group, a ketone group, a urethane group, a silyl group, a sulfoxide group or a combination thereof,R₅, R₆, R₇, R₈, R₉ and R₁₀ are, each one and independently, hydrogen, hydroxyl or an —OR,′ group, where R₄ is a protector group according to the previous definition; andb) at least one chemotherapeutic agent, suitable for use in the treatment of Breast Cancer.