NANOPARTICLE CONTRAST AGENT FOR EARLY DIAGNOSIS OF ALZHEIMER'S DISEASE BY MAGNETIC RESONANCE IMAGING (MRI)

摘要

The disclosure herein relates to a novel nanoparticle that can cross the blood-brain barrier and form a bond with amyloid plaques and other related protein aggregates for detection by magnetic resonance imaging (MRI). The compositions, methods of making, and methods of use set forth herein also provide a non-invasive means for diagnosing Alzheimer's disease at an early stage.