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Increase Production of Isoprenoids in Saccharomyces Cerevisiae by Carotenoid Optimization and Screening

机译：通过类胡萝卜素优化和筛选提高酿酒酵母中类异戊二烯的产量

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摘要

The invention is for an increased isoprenoid production by carotenoid optimization in an expression system and the carotegenic gene for optimization may be geranylgeranyl diphosphate synthase (GGPPS), phytoene synthase (PSY1), conserved CRTI or mutated CRT1_A393T, BT1 of S. cerevisae. The carotogenic gene from red yeast which includes Rhodosporidium spp. Rhodotorula spp, Sporidiobolus spp., Leucosporidium spp., Sporobolomyes spp. is selected.

机译：本发明是通过在表达系统中通过类胡萝卜素优化来增加类异戊二烯的产生，并且用于优化的胡萝卜素基因可以是香叶基香叶基二磷酸合酶（GGPPS），八氢番茄红素合酶（PSY1），保守的CRTI或突变的CRT 1 < Sub> A393T ， S的BT 1 。酿酒科。来自红色酵母的致癌基因，其中包括 Rhodosporidium spp。 Rhodotorula spp， Sporidiobolus spp。， Leucosporidium spp。， Sporobolomyes spp。被选中。 展开▼

著录项

公开/公告号US2017198310A1

专利类型

公开/公告日2017-07-13

原文格式PDF

申请/专利权人 INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH;
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申请/专利号US201615066296

发明设计人 ANAND KUMAR BACHHAWAT;MANISHA WADHWA;
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申请日2016-03-10

分类号C12P5/00;C12N15/81;C12N9/88;C12N15/52;

国家 US

入库时间 2022-08-21 13:52:41

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