INCREASED PRODUCTION OF ISOPRENOIDS IN SACCHAROMYCES CEREVISIAE BY CAROTENOID OPTIMIZATION AND SCREENING

摘要

The invention is for an increased isoprenoid production by carotenoid optimization in an expression system and the carotegenic gene for optimization may be geranylgeranyl diphosphate synthase (GGPPS), phytoene synthase (PSY1), conserved CRT1 or mutated CRT1A393T» BTSl of S.cerevisae. The carotogenic gene from red yeast which includes Rhodosporidium spp. Rhodotorula spp, Sporidiobolus spp., Leucosporidium spp., Sporobolomyes spp. is selected. H2