ASSEMBLY OF LAYERED MONETITE-CHITOSAN NANOCOMPOSITE AND ITS TRANSITION TO ORGANIZED HYDROXYAPATITE

摘要

A multilayer structure that functions as a bone replacement material includes a plurality of organic matrix layers such that each organic matrix layer includes chitosan and a dicarboxylic acid. The multilayer structure also includes a plurality of calcium phosphate-containing layers wherein each calcium phosphate-containing layer is interposed between a pair of organic matrix layers. Characteristically, the chitosan is cross-linked by the dicarboxylic acid.