Integrated Multi-modal Imaging and Sensing Techniques to Enable Portable, Label-free, High-specificity, and Scalable Biosensors

摘要

An analyte monitoring device is provided that includes a microfluidic channel, where the microfluidic channel is configured for holding a sample under test, an electromagnetic excitation source disposed on a first side of the microfluidic channel, an ultrasonic transducer disposed on a second side of the microfluidic channel, or disposed on the first side of the microfluidic channel, and an appropriately programmed computer, where the electromagnetic excitation source is disposed to induce an thermoacoustic response in the microfluidic channel when holding the sample under test, where the ultrasonic transducer is disposed to receive the thermoacoustic response, where the ultrasonic transducer outputs a voltage to the appropriately programmed computer, where the appropriately programmed computer outputs an analyte value according to the thermoacoustic response.