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MODULATION OF ESTROGEN RECEPTOR-RELATED RECEPTOR GAMMA (ERR GAMMA) AND USES THEREFOR

机译:雌激素受体相关受体γ(ERR GAMMA)的调节及其用途

摘要

This application provides methods of increasing vascularization, muscle performance, muscle rehabilitation, and/or mitochondrial activity in subjects in need thereof, by administering a therapeutically effective amount of one or more agents that increases ERRγ activity to the subject. Such agents can include one or more ERRγ agonists. In some examples the method does not require that the subject exercise, and as such, the subject may be sedentary (such as bedridden or in a wheelchair).
机译:本申请提供了通过向受试者施用治疗有效量的一种或多种增加ERRγ活性的试剂来增加有需要的受试者的血管生成,肌肉性能,肌肉康复和/或线粒体活性的方法。这样的试剂可以包括一种或多种ERRγ激动剂。在一些示例中,该方法不需要受试者运动,并且因此受试者可以是久坐的(例如卧床不起或坐在轮椅上)。

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