首页> 外国专利> RECOMBINANT POLYPEPTIDE FOR PROMOTING SCARLESS WOUND HEALING AND BIOADHESIVE MATERIAL INCLUDING THE SAME

RECOMBINANT POLYPEPTIDE FOR PROMOTING SCARLESS WOUND HEALING AND BIOADHESIVE MATERIAL INCLUDING THE SAME

机译:重组多肽,用于促进无疤痕愈合和生物吸收性物质,包括相同的物质

摘要

Provided are a recombinant polypeptide in which a small leucine-rich proteoglycan mimetic sequence is attached to a terminal of a mussel adhesive protein, a composition for wound healing including the same, a bioadhesive material, and a preparation method thereof. According to the present disclosure, the recombinant polypeptide in which the small leucine-rich proteoglycan mimetic sequence is attached to the terminal of the mussel adhesive protein has an excellent epidermal regeneration effect in which the wound site is uniformly restored by promoting rapid wound healing at the wound site when being applied to the wound site and inducing formation of collagens which are arranged and concentrated at the wound site, and thus can be usefully used as various drugs, cosmetics, and quasi-drugs.
机译:本发明提供一种重组多肽,其在贻贝粘附蛋白的末端连接有富含亮氨酸的小蛋白聚糖模拟序列,包括伤口愈合的组合物,生物粘附材料及其制备方法。根据本公开,其中富含亮氨酸的小蛋白聚糖小序列模拟序列附着于贻贝粘附蛋白的末端的重组多肽具有优异的表皮再生效果,其中通过促进伤口处的快速伤口愈合而均匀地恢复了伤口部位。当应用于伤口部位时,该伤口部位可以诱导胶原蛋白的形成,胶原蛋白在伤口部位排列并浓缩,因此可以有效地用作各种药物,化妆品和准药物。

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