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Normalization of the enterohepatic circulation in animals with a chimeric humanized liver
Normalization of the enterohepatic circulation in animals with a chimeric humanized liver
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机译:嵌合人源化肝动物中的肝肠循环正常化
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摘要
Methods of normalizing bile acid production in a mouse engrafted with human hepatocytes by the administration of human FGF19 are disclosed. Also disclosed is a transgenic host animal, such as a mouse, that expresses human FGF19 that has normalized bile acid production when engrafted with human hepatocytes.
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