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Real time electronic cell sensing systems and applications for cell-based assays
Real time electronic cell sensing systems and applications for cell-based assays
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机译:实时电子细胞传感系统及其在基于细胞的测定中的应用
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摘要
The present invention includes devices, systems, and methods for assaying cells using cell-substrate impedance monitoring. In one aspect, the invention provides cell-substrate impedance monitoring devices that comprise electrode arrays on a nonconducting substrate, in which each of the arrays has an approximately uniform electrode resistance across the entire array. In another aspect, the invention provides cellular assays that use impedance monitoring to detect changes in cell behavior or state. In some preferred aspects, the assays are designed to investigate the affects of compounds on cells, such as cytotoxicity assays.
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