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METHOD FOR CONSTRUCTING QUADRANTS WITH MULTIPLE INDEPENDENT BIOMARKERS FOR DIAGNOSING DISEASES
METHOD FOR CONSTRUCTING QUADRANTS WITH MULTIPLE INDEPENDENT BIOMARKERS FOR DIAGNOSING DISEASES
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机译:用于诊断疾病的具有多个独立生物标志物的数量的方法
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摘要
The present invention relates to a method for constructing quadrants corresponding to different diseases in a frame of concentrations of multiple independent biomarkers, comprising:(a) transferring original distributed concentrations of every independent biomarker to modified distributed concentrations, comprising: calculating the mean value and the standard deviation of the original distributed concentrations for a given independent biomarker;individually subtracting all the original distributed concentrations by the mean value for the given independent biomarker; andindividually dividing all the differences by the standard deviation to get the modified distributed concentrations for the given independent biomarker;(b) positing the modified distributed concentrations in a frame of multiple independent biomarkers; and(c) finding a boundary optimally separating neighboring quadrants corresponding to different diseases.展开▼