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Adenovirus derived helper virus for enhancing recombinant parvovirus production
Adenovirus derived helper virus for enhancing recombinant parvovirus production
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机译:腺病毒衍生的辅助病毒,用于增强重组细小病毒的生产
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摘要
Described is an adenovirus derived helper virus which may comprise the adenoviral DNA sequences for E2a, S4 (orf6), the VA1 RNA gene, and the parvovirus VP capsid gene unit. Also described is a method of efficiently preparing a recombinant parvovirus (particle) which is based on the use of various adenoviral derived helper viruses/vectors.
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