首页>
外国专利>
Microarray-based assay integrated with particles for analyzing molecular interactions
Microarray-based assay integrated with particles for analyzing molecular interactions
展开▼
机译:基于微阵列的分析与颗粒相结合,用于分析分子相互作用
展开▼
页面导航
摘要
著录项
相似文献
摘要
A microarray-based assay is provided, which is used for analyzing molecular interactions, including polynucleotides, polypeptides, antibodies, small molecule compounds, peptides and carbohydrates. Such method comprises coupling a target molecule to a particle and then binding to a probe molecule on microarray. In particular, multiplexed genetic analysis of nucleic acid fragments can be implemented. Specific genes, single nucleotide polymorphisms or gene mutations, such as deletions, insertions, and indels, can be identified. Coupled with microarray, the particles, themselves or further modified, facilitate the detection of results with non-expensive devices or even naked eyes. This technology enables the detection and interpretation of molecular interactions in an efficient and cost effective way.
展开▼